Alpha-fetoprotein (AFP) test cost in Sioux Falls, SD

Prices at 3 hospitals in Sioux Falls, SD, from their machine-readable files. Here the median cash price is $189 — 117% above the US median ($87), roughly 11.3× the Medicare rate.

Lowest cash prices

HospitalLocationCashInsurerCMS ratingER waitReadmit
Sioux Falls Specialty Hospital Sioux Falls, SD $156 $137 — — —
Avera Heart Hospital of South Dakota Sioux Falls, SD $221 $128 ★ 5/5 110 min —

CMS rating = overall hospital star rating (1–5); ER wait = median minutes in the emergency department; Readmit = 30-day readmission rate (lower is better) — all from Medicare’s Care Compare; “—” = not reported. Data last updated October 2026. Prices from hospitals’ machine-readable files (45 CFR §180); Medicare benchmark from CMS PFS/CLFS/IPPS. Prices below 15% of the median are excluded as likely partial or mis-coded charges. Estimates — confirm with the hospital. Report an incorrect price.

Price comparison (median)

Chargemaster (list price)
$191
Cash / self-pay
$189
Insurer-negotiated
$128
Medicare pays
$17
$163$215
Median cash $189  ·  Medicare $17  ·  bar = typical cash range (10th–90th percentile)
Is this a fair price?
1× Medicarefair ≈2×5×+

Typical cash price here is $189 — about 11.3× the Medicare rate ($17). High vs Medicare. A fair cash price is usually within ~2× Medicare ($34).

💡 Asking for the cash price instead of the $191 list price could save about $2 (1%).

Estimate what you’ll pay
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Rough estimate from this procedure’s median insurer-negotiated rate. Your actual cost depends on your plan — confirm with your insurer.

All Alpha-fetoprotein (AFP) test prices in South Dakota → · All Alpha-fetoprotein (AFP) test prices (national) · All hospitals in Sioux Falls