Alpha-fetoprotein (AFP) test cost in South Dakota

Prices at 40 hospitals in South Dakota, from their machine-readable files. Here the median cash price is $152 — 75% above the US median ($87), roughly 9.1× the Medicare rate.

Lowest cash prices

HospitalLocationCashInsurerCMS ratingER waitReadmit
Dunes Surgical Hospital Dakota Dunes, SD $27 $31 — — —
Hans P Peterson Memorial Hospital-CAH Philip, SD $62 $60 — 88 min —
Monument Health Spearfish Hospital Spearfish, SD $78 $49 ★ 4/5 144 min —
Sanford Canton-Inwood Medical Center-CAH Canton, SD $82 $76 — 124 min —
Faulkton Area Medical Center Faulkton, SD $93 $98 — 122 min —
Bowdle Hospital-CAH Bowdle, SD $106 $95 — 102 min —
Community Memorial Hospital Redfield, SD $108 $121 ★ 4/5 102 min —
Monument Health Rapid City Hospital Rapid City, SD $115 $88 ★ 3/5 172 min —
Avera St Lukes Aberdeen, SD $119 $115 ★ 4/5 126 min —
Milbank Area Hospital/avera Health Milbank, SD $119 $115 — 126 min —
Brookings Health System Brookings, SD $128 $100 ★ 4/5 97 min —
Avera St Mary's Hospital Pierre, SD $130 $98 ★ 2/5 127 min —
St Michael's Hospital-CAH Tyndall, SD $131 $122 — 112 min —
Sanford Clear Lake Medical Center Clear Lake, SD $134 $138 — 93 min —
Sanford Hospital Webster-CAH Webster, SD $134 $124 — 110 min —
Avera Hand County Memorial Hospital and Clinic Miller, SD $139 $120 — 111 min —
Avera Sacred Heart Hospital Yankton, SD $146 $131 ★ 3/5 117 min —
Avera Gregory Hospital Gregory, SD $146 $131 — 139 min —
Monument Health Sturgis Hospital Sturgis, SD $152 $77 — 132 min —
Monument Health Custer Hospital Custer, SD $152 $93 — 132 min —
Sanford Chamberlain Medical Center Chamberlain, SD $154 $140 — 80 min —
Sioux Falls Specialty Hospital Sioux Falls, SD $156 $137 — — —
Avera Queen of Peace Mitchell, SD $175 $123 ★ 4/5 104 min —
Marshall County Healthcare Center-CAH Britton, SD $176 $115 — 105 min —
Avera Weskota Memorial Medical Center-CAH Wessington Springs, SD $176 $163 — 126 min —

CMS rating = overall hospital star rating (1–5); ER wait = median minutes in the emergency department; Readmit = 30-day readmission rate (lower is better) — all from Medicare’s Care Compare; “—” = not reported. Data last updated October 2026. Prices from hospitals’ machine-readable files (45 CFR §180); Medicare benchmark from CMS PFS/CLFS/IPPS. Prices below 15% of the median are excluded as likely partial or mis-coded charges. Estimates — confirm with the hospital. Report an incorrect price.

Price comparison (median)

Chargemaster (list price)
$167
Cash / self-pay
$152
Insurer-negotiated
$123
Medicare pays
$17
$89$295
Median cash $152  ·  Medicare $17  ·  bar = typical cash range (10th–90th percentile)
Is this a fair price?
1× Medicarefair ≈2×5×+

Typical cash price here is $152 — about 9.1× the Medicare rate ($17). High vs Medicare. A fair cash price is usually within ~2× Medicare ($34).

💡 Asking for the cash price instead of the $167 list price could save about $15 (9%).

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Rough estimate from this procedure’s median insurer-negotiated rate. Your actual cost depends on your plan — confirm with your insurer.

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Alpha-fetoprotein (AFP) test cost in other states

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