Chemotherapy infusion (first hour) cost in South Dakota

Prices at 34 hospitals in South Dakota, from their machine-readable files. Here the median cash price is $798 — 33% above the US median ($601), roughly 6.0× the Medicare rate.

Lowest cash prices

HospitalLocationCashInsurerCMS ratingER waitReadmit
Brookings Health System Brookings, SD $381 $426 ★ 4/5 97 min —
Faulkton Area Medical Center Faulkton, SD $451 $476 — 122 min —
Avera Dells Area Hospital-CAH Dell Rapids, SD $455 $373 — 106 min —
Dunes Surgical Hospital Dakota Dunes, SD $518 $447 — — —
Avera Sacred Heart Hospital Yankton, SD $630 $562 ★ 3/5 117 min —
Avera Gregory Hospital Gregory, SD $630 $562 — 139 min —
Avera Weskota Memorial Medical Center-CAH Wessington Springs, SD $642 $597 — 126 min —
Winner Regional Healthcare Center-CAH Winner, SD $672 $571 — 109 min —
Sanford Canton-Inwood Medical Center-CAH Canton, SD $674 $619 — 124 min —
Platte Health Center Platte, SD $682 $620 — 128 min —
Community Memorial Hospital Redfield, SD $689 $770 ★ 4/5 102 min —
Sanford Medical Center Aberdeen Aberdeen, SD $720 $619 ★ 4/5 120 min —
Sioux Falls Specialty Hospital Sioux Falls, SD $759 $667 — — —
Avera St Lukes Aberdeen, SD $760 $734 ★ 4/5 126 min —
Milbank Area Hospital/avera Health Milbank, SD $760 $734 — 126 min —
Sanford Usd Medical Center Sioux Falls, SD $768 $421 ★ 5/5 207 min —
Avera Flandreau Hospital-CAH Flandreau, SD $798 $602 — 108 min —
Avera Hand County Memorial Hospital and Clinic Miller, SD $798 $693 — 111 min —
Avera St Mary's Hospital Pierre, SD $823 $625 ★ 2/5 127 min —
Sanford Clear Lake Medical Center Clear Lake, SD $829 $855 — 93 min —
Douglas County Memorial Hospital-CAH Armour, SD $858 $932 — 118 min —
St Michael's Hospital-CAH Tyndall, SD $861 $801 — 112 min —
Hans P Peterson Memorial Hospital-CAH Philip, SD $873 $851 — 88 min —
Monument Health Rapid City Hospital Rapid City, SD $877 $645 ★ 3/5 172 min —
Monument Health Sturgis Hospital Sturgis, SD $877 $851 — 132 min —

CMS rating = overall hospital star rating (1–5); ER wait = median minutes in the emergency department; Readmit = 30-day readmission rate (lower is better) — all from Medicare’s Care Compare; “—” = not reported. Data last updated October 2026. Prices from hospitals’ machine-readable files (45 CFR §180); Medicare benchmark from CMS PFS/CLFS/IPPS. Prices below 15% of the median are excluded as likely partial or mis-coded charges. Estimates — confirm with the hospital. Report an incorrect price.

Price comparison (median)

Chargemaster (list price)
$877
Cash / self-pay
$798
Insurer-negotiated
$708
Medicare pays
$133
$552$996
Median cash $798  ·  Medicare $133  ·  bar = typical cash range (10th–90th percentile)
Is this a fair price?
1× Medicarefair ≈2×5×+

Typical cash price here is $798 — about 6.0× the Medicare rate ($133). High vs Medicare. A fair cash price is usually within ~2× Medicare ($267).

💡 Asking for the cash price instead of the $877 list price could save about $79 (9%).

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Rough estimate from this procedure’s median insurer-negotiated rate. Your actual cost depends on your plan — confirm with your insurer.

Chemotherapy infusion (first hour) cost in other states

All Chemotherapy infusion (first hour) prices (national) → · All hospitals in South Dakota →