Chemotherapy infusion cost in South Dakota

Prices at 34 hospitals in South Dakota, from their machine-readable files. Here the median cash price is $537 — 29% above the US median ($418), roughly 6.6× the Medicare rate.

Lowest cash prices

HospitalLocationCashInsurerCMS ratingER waitReadmit
Brookings Health System Brookings, SD $214 $355 ★ 4/5 97 min —
Avera Dells Area Hospital-CAH Dell Rapids, SD $274 $111 — 106 min —
Dunes Surgical Hospital Dakota Dunes, SD $313 $438 — — —
Faulkton Area Medical Center Faulkton, SD $369 $312 — 122 min —
Avera Weskota Memorial Medical Center-CAH Wessington Springs, SD $412 $309 — 126 min —
Platte Health Center Platte, SD $422 $303 — 128 min —
Community Memorial Hospital Redfield, SD $430 $391 ★ 4/5 102 min —
Sanford Canton-Inwood Medical Center-CAH Canton, SD $436 $255 — 124 min —
Avera Sacred Heart Hospital Yankton, SD $442 $338 ★ 3/5 117 min —
Avera Gregory Hospital Gregory, SD $442 $338 — 139 min —
Sioux Falls Specialty Hospital Sioux Falls, SD $455 $330 — — —
Avera St Lukes Aberdeen, SD $475 $215 ★ 4/5 126 min —
Milbank Area Hospital/avera Health Milbank, SD $475 $215 — 126 min —
Douglas County Memorial Hospital-CAH Armour, SD $501 $186 — 118 min —
Winner Regional Healthcare Center-CAH Winner, SD $507 $364 — 109 min —
Sanford Medical Center Aberdeen Aberdeen, SD $510 $337 ★ 4/5 120 min —
Avera Hand County Memorial Hospital and Clinic Miller, SD $529 $394 — 111 min —
Marshall County Healthcare Center-CAH Britton, SD $546 $278 — 105 min —
Sanford Clear Lake Medical Center Clear Lake, SD $555 $327 — 93 min —
Hans P Peterson Memorial Hospital-CAH Philip, SD $577 $536 — 88 min —
Avera St Mary's Hospital Pierre, SD $577 $297 ★ 2/5 127 min —
Sanford Usd Medical Center Sioux Falls, SD $581 $342 ★ 5/5 207 min —
Wagner Community Memorial Hospital-CAH Wagner, SD $599 $465 — 114 min —
Sanford Chamberlain Medical Center Chamberlain, SD $611 $329 — 80 min —
Monument Health Rapid City Hospital Rapid City, SD $637 $357 ★ 3/5 172 min —

CMS rating = overall hospital star rating (1–5); ER wait = median minutes in the emergency department; Readmit = 30-day readmission rate (lower is better) — all from Medicare’s Care Compare; “—” = not reported. Data last updated October 2026. Prices from hospitals’ machine-readable files (45 CFR §180); Medicare benchmark from CMS PFS/CLFS/IPPS. Prices below 15% of the median are excluded as likely partial or mis-coded charges. Estimates — confirm with the hospital. Report an incorrect price.

Price comparison (median)

Chargemaster (list price)
$584
Cash / self-pay
$537
Insurer-negotiated
$340
Medicare pays
$81
$382$716
Median cash $537  ·  Medicare $81  ·  bar = typical cash range (10th–90th percentile)
Is this a fair price?
1× Medicarefair ≈2×5×+

Typical cash price here is $537 — about 6.6× the Medicare rate ($81). High vs Medicare. A fair cash price is usually within ~2× Medicare ($162).

💡 Asking for the cash price instead of the $584 list price could save about $46 (8%).

Estimate what you’ll pay
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Rough estimate from this procedure’s median insurer-negotiated rate. Your actual cost depends on your plan — confirm with your insurer.

Chemotherapy infusion cost in other states

All Chemotherapy infusion prices (national) → · All hospitals in South Dakota →